Efficient assembly of oligomannosides using the hydrophobically assisted switching phase method.

نویسندگان

  • Shuai Meng
  • Tian Tian
  • Dong Han
  • Lin-Na Wang
  • Shao-Geng Tang
  • Xiang-Bao Meng
  • Zhong-Jun Li
چکیده

The hydrophobically assisted switching phase (HASP) method was applied in the assembly of oligomannosides. A new mannosyl donor with high reactivity was selected after a series of optimization studies, which was suitable for the synthesis of oligomannosides via the HASP method. The practicability of the HASP method towards the synthesis of branched oligosaccharides was explored and two branched penta-mannosides were assembled efficiently.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 13 24  شماره 

صفحات  -

تاریخ انتشار 2015